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About Genetic Selection


Genetic selection procedures are done either on fetuses, through prenatal screening, or on embryos that are outside a woman’s body, through Preimplantation Genetic Diagnosis (PGD).

PGD tests embryos for the presence of genetic sequences linked to a variety of conditions and characteristics. A cell is extracted from an embryo at its eight-cell stage and analyzed. Embryos with the selected characteristics can be implanted in a woman's uterus to develop into a child. The procedure does not appear to affect embryos’ or fetuses’ subsequent development, though more follow-up studies of children born after PGD are needed.


Frequently Asked Questions

Arguments Pro & Con

PGD was developed to allow couples at risk of passing on a serious genetic disease to have children not affected by it. Since its introduction in 1990, it has been most widely used to prevent the birth of children with conditions such as Down's syndrome, Tay-Sachs disease, cystic fibrosis, sickle cell, Huntington's chorea, and Cooley's anemia.

However, PGD is increasingly being used for other reasons. These include social sex selection, creating “savior siblings” who can provide bone marrow or other transplant tissues to sick older siblings, and selecting against embryos with genes correlated with late-onset and non-fatal conditions.

A newer variation of PGD, called Preimplantation Genetic Haplotyping, allows for many more genes to be tested, and for greater accuracy.

Many disability rights advocates, in particular, have been critical of PGD and prenatal screening. They point out that the definition of "disease" is to some extent subjective. Most support women’s right to decide whether or not to have a child at a given time, but are critical of basing this decision on the traits of the particular embryo or fetus.



Experts Fear Potential Abuses of Genetic Screeningby Beth WhitehouseNewsdayJuly 18th, 2008Will parents use embryo selection technology to select a child's characteristics the way you can pick the options on a car?
Kiwis consider sex selectionby Jesse ReynoldsBiopolitical TimesJune 20th, 2008The New Zealand Bioethics Council recommended allowing prospective parents to use sex selection through PGD for family balancing.
Is Sex Necessary for Reproduction?[Quotes CGS's Marcy Darnovsky]by Bernadette TanseySan Francisco ChronicleJune 1st, 2008The in vitro fertilization industry, which originated in the 1980s as a solution for infertile couples, has actively sought to expand its market scope by tapping social trends and collaborating with researchers in genetics and stem cell technology.
Dutch Cabinet Crisis Averted... For NowJust a storm in a test tube?by RNW's Dutch serviceRadio Netherlands WorldwideMay 31st, 2008Dutch Prime Minister Jan Peter Balkenende's fourth cabinet has narrowly avoided its first internal crisis caused by the domestic practice of carrying out tests for certain genetic defects on embryos during IVF treatment.
MPs Reject 'Saviour Sibling' BanBBC NewsMay 23rd, 2008A bid to stop parents having "saviour siblings" - babies selected to provide genetic material for seriously ill relatives - has been defeated by the United Kingdom Parliament.
Robert Winston on the UK's fertility billby Jesse ReynoldsBiopolitical TimesMay 13th, 2008Assisted reproduction pioneer Lord Robert Winston had some surprising words about the UK's controversial bill to overhaul its oversight of the reproduction industry and stem cell research.
Embryo research: a source of hope or horror?by Roger HighfieldThe Telegraph (UK)May 9th, 2008As the United Kingdom Parliament prepares to debate a Bill revising the law on embryo research, Telegraph Science Editor Roger Highfield examines the complex issues at stake.
Sex selection: On sale hereby Marcy DarnovskyBiopolitical TimesApril 24th, 2008A discount offer - on an ethically sketchy and unnecessary invasive procedure.
Couples Could Win Right to Select Deaf Babyby Richard GrayTelegraphApril 14th, 2008Deaf couples could be allowed to use embryo-screening technology and choose to have a deaf child, after an amendment to a controversial bill to overhaul the UK's oversight of ARTs.
Is it wrong to select a deaf embryo?by Clare MurphyBBC NewsMarch 10th, 2008New fertility legislation will make it illegal to use embryos with a known genetic abnormality in IVF treatment when ones without the same defect are available.
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